US Patent 8,605,981, titled “Centromere detector and method for determining radiation exposure from chromosome abnormalities,” has been issued to Peter K. Rogan, Joan H. Knoll, Jagath Samarabandu, and Akila Subasinghe. The patent is assigned to Cytognomix. The inventors have developed Automated Dicentric Chromosome Identifier (ADCI) software based on this technology. The present version of ADCI runs threaded on a multi-CPU desktop PC, and has been parallelized for high throughput processing on a number of multi-core systems, including IBM’s BlueGene/Q. We have achieved high throughput of automated chromosome-based biodosimetry analysis, completing processing of images from 1000 samples in an hour with this hardware platform.
We find and validate mutations that others cannot