Tag Archives: 4qtel

Subtelomeric SC-FISH probes Catalog

Probes to detect subtelomeric imbalances

These probes are closer to chromosome termini than competitor products. Click to see the Gallery of scFISH images

  Chr. Target   scFISH probes1  Competitor Recombinant probes2
Catalog Number Chr
 Length(bp) Distance from Telomere (kb)3  Estimated clone size Approx distance of STS from telomere (kb)4
ST-0000101 1ptel 2531* 1,045.411 – 1,047.942 90 kb unknown
3930* 1,048.515 – 1,052.445
ST-0000102 1ptel
3512* 1,053.361 – 1,056.873
ST-0000103 1ptel
2671 3,858.025 – 3,860.694
ST-0000104 1ptel
1853 7,939.921 – 7,941.773 100 kb 236 ± 100
ST-0000105 1qtel
ST-0000106 1qtel 1632* 97.847 – 96.215
2503 89.194-86.692
ST-0000107 1qtel
2653 175 kb 322 ± 175
ST-0000108 2ptel 112.585 – 115.237
3355 2,398.933 – 2,402.287 60 kb 390 ± 46
ST-0000109 2qtel
ST-0000110 3ptel 2093* 181.265-183..325 80 kb 248 ± 80
1834* 199.161-200..994
ST-0000111 3ptel
2953 762.774 – 765.726 95 kb6 997 ± 95
ST-0000112 3qtel
2022*
ST-0000113 3qtel 595.753 – 593.731
ST-0000114 4ptel 1796 246.384 – 248.179; 417.863 – 419.7107 145 kb6 (220-292) ± 73
2426 442.967 – 445.387 130 kb 930 ± 130
ST-0000115 4qtel
ST-0000116 5ptel 2189 86.825 – 89.013 191kb unknown
2795 2,032.602 – 2,035.396 105 kb 227 ± 105
ST-0000117 5qtel
ST-0000118 5qtel 2661 2,019.454 – 2,022.114
ST-0000119 5qtel 2633* 627.290 – 624.657
ST-0000120  5qtel 1753* 422.516 – 420.763
ST-0000121 6ptel 2152 199.487 – 201.638 80 kb unknown
2554 175.551 – 178.104 100 kb (276-282) ± 94
ST-0000122 6qtel
ST-0000123 7ptel 2872 815.565 – 818.439 60 kb 218 ± 59
2434*
ST-0000124 7ptel 143.257 – 145.691
2348*
ST-0000125 7ptel 146.749 – 149.097
2574 1,095.575 – 1,098.148 95 kb 225 ± 95
ST-0000126 7qtel
1517*
ST-0000127 7qtel 28.945 – 27.428
1634*
ST-0000128 7qtel 5.405 – 3.771
1865*
ST-0000129 7qtel 81.313 – 79.448
ST-0000130 8ptel 2079 483.728 – 485.805 135 kb 1,200 ± 135

 

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Customized scFISH probes

Snapshots of predesigned SC-FISH probes from selected regions of chromosomes 9 and 17

Customized single copy FISH probes can detect small rearrangements in chromosomes with precision, without compromising sensitivity or specificity. Useful for chromosome breakpoint delineation or confirmation of subtle rearrangements suggested by other techniques.

Features

Probes pre-designed for ~223,000 genomic intervals (average genomic resolution ~15 kb)
Available labeled or unlabeled
No Cot-1 or blocking DNA required
Probes detect 100 fold smaller genomic targets than  conventional FISH probes. Sizes range from 1.5 to 10 kb
Often multiple probes per gene available
Probes detect rearrangements in small genes
Probe validation by nested PCR or other rapid hybridization methods. Optional FISH validation available.
All probes have been validated by FISH
Research Use Only
Covered by  US Pat. No 7,734,424,   8,209,129, and 8,407,013

A subscription to our  MutationForecaster system provides genome browser access to our genome-wide custom probe designs through the  cytogenetic Visual Analytics Decision Support Tool. This tool displays the locations of all of our custom FISH products. Or, contact us for the probes you are looking for.